Human neuron subtype programming through combinatorial patterning with scSeq readouts
Organism
Homo sapiens
Samples
21 samples
Published
Jul 15, 2025
Platform
30173;24676
Type
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Entry Type
GSE
Summary
iPSCs were induced into neuronal fate using either NGN2 or ACL1/DLX2 under different conditions. Single-cell RNA-sequencing was used to measure diversity of acquired neuronal fates. Single-cell multiome (RNA+ATAC) was performed on patterned iPSCs.