Single-cell transcriptomics of the Drosophila ring gland identifies SoxN–Vvl complex as key regulator of juvenile hormone biosynthesis

Summary

We have employed a single cell sequencing approach using 10x Genomics scRNA-seq to elucidate the transcriptional landscape of the Drosophila larval corpus allatum (CA). As a a sub-organ within the ring gland, the CA expresses a set of enzymes that mediate steps in the conversion of acetyl-CoA into JH. This study provide single-cell sequencing data of the larval ring gland at early wandering stage, and found that CA-specific expressing SoxN is required for juvenile hormone biosynthesis and metamorphosis.

Details

Organism

Drosophila melanogaster

Samples

1 sample

Publication Date

Jan 20, 2026

Platform

21306

Entry Type

GSE

Identifier