Achieving CD8+ T cell-dependent lethality by targeting cancer USP14 in HCC [CRISPR screen]
Organism
synthetic construct
Samples
4 samples
Published
Nov 14, 2025
Platform
21616
Type
Other
Entry Type
GSE
Summary
Using the CRISPR genome editing system and a cancer cell/activated CD8+ T cell co-culture system, we identified the key genes in HCC cells that enhanced HCC cell tolerance to CD8+ T cells.